Objective To investigate the correlation between the calcaneus bone mineral densities measured by two different quantitative ultrasound bone densitometries. Methods A total of 479 female adult were randomly selected from Guangxi. Achilles Express (AE)quantitative ultrasound bone densitometry（USA）and SONOST 3000 (SN) (Korea) were used to measure calcaneus bone mineral densities the right side. Results (1)Comparison of measurement results:Tf score and stiffness index (SI) measured by AE were higher SN (P<0.01). (2)Correlation of measurement results: T score and SI measured by two quantitative ultrasound bone densitometries were significant positive linear correlated (P<0.01),the linear regression equations were: TSN=0.533*TAE -1.661，SISN=0.605*SIAE-5.493. (3)The rates of osteoporosis detected by AE and SN were 3.8% and 17.7%，respectively.The results were consistent and statistically significant (P<0.01),but they also had statistical differences(P<0.01). Conclusion There is correlation between the results measured by AE and SN. However, there are also significant differences.Therefore,the results measured by the representative and widely used instruments need to be transformed according to internationally gold standard “dual energy X-ray” in order to accurately evaluate the effect of ultrasound bone densitometry in diagnosing, preventing and screening osteoporosis,and to achieve the purpose of data calibration.