解剖学报

›› 2009, Vol. 40 ›› Issue (2): 283-287.doi: 10.3969/j.issn.0529-1356.2009.02. 023

• 论著 • 上一篇    下一篇

盖膜与内毛细胞静纤毛相互作用的生物力学分析

杨琳1,2; 戴培东2*; 华诚1* ;张天宇2 ;丁光宏1 ;王克强1,3 ;王正敏2   

  1. 1.复旦大学力学与工程科学系，上海 200433;2.复旦大学附属眼耳鼻喉科医院中心实验室，上海 200031;3.复旦大学附属中山医院心血管病研究所，上海 200032
  • 收稿日期:2008-04-16 修回日期:2008-06-12 出版日期:2009-04-06
  • 通讯作者: 戴培东;华诚

Mechanical analysis of interaction between tectorial membrane and inner hair cell stereocilia

  1. 1. Department of Mechanics and Engineering Science, Fudan University, Shanghai 200433, China; 2. Central Laboratory, Eye and ENT Hospital of Fudan University, Shanghai 200031,China；3. Institute of Cardiovascular Disease, Zhongshan Hospital of Fudan University, Shanghai 200032, China
  • Received:2008-04-16 Revised:2008-06-12 Online:2009-04-06
  • Contact: DAI Pei-dong; HUA Cheng

关键词: 盖膜, 内毛细胞, 静纤毛, 有限元分析, 豚鼠

Abstract: Objective To investigate the interaction between tectorial membrane and inner hair cell stereocilia in the condition of vibration of the organ of Corti. Methods Two-2D finite-element models were built based on the electron microscopic images of the organ of Corti from the guinea pig with two models of coupled and non-coupled between the tectorial membrane and stereocilia. ANSYS software was used to analyze the two models. Results When Couette flow was loaded, the stereocilia had a larger angular displacement in non-coupled manner, Von Mises stress were higher on tip link and rootlet, and the characteristics of natural frequency were quite similar on two models.Conclusions The stereocilium is excited easily when it does not contact the tectorial membrane.

Key words: Tectorial membrane, Inner hair cell, Stereocilia, Finite element analysis, Guinea pig

中图分类号: