Transplantation studies of induced pluripotent stem cells at different differentiated stages

doi:10.16098/j.issn.0529-1356.2015.05.022

Abstract

Abstract:

Induced pluripotent stem cells (iPSCs) which derived from reprogrammed somatic cells, are totipotential cells similar to embryonic stem cells. Recently, iPSCs technology has been promptly improved in methods of induction and in vitro differentiation. Consequently, iPSCs at different differentiated stages have been widely studied in cell transplantation experiments. Here, we summarize the current studies of iPSCs transplantation, and reviewe some novel methods comparing with the older one. We propose that some problems need to be resolved before iPSCs could be applied in clinic therapy.

Key words: induced pluripotent Induced pluripotent stem cell, Blastocyst complementation, Organ bud

LI Jun DU Xiao WU Yan-shuang LEI Lei*. Transplantation studies of induced pluripotent stem cells at different differentiated stages[J]. AAS, 2015, 46(5): 699-703.

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