Related research progress of autophagy in cervical cancer cells

doi:10.16098/j.issn.0529-1356.2017.01.020

Abstract

Abstract:

Cell autophagy refers to use lysosomes to degrade the misfolded proteins and the damaged organelles in the cytoplasm. This process can reuse the intracellular degradation substances in order to maintain stable environment in the cell.Normal cells maintain at a low level of autophagy. When a cell is under the condition of unfavorable factors， its autophagy can be activated against unfavorable factors.Autophagy plays an important role in cancer occurrence,development, metastasis, recurrence and drug resistance, but the detailed mechanism of autophagy in these areas is still unclear.In this paper, the autophagy\| related genes in cervical cancer cells and their application in cervical cancer treatment are reviewed.

Key words: Cervical cancer, Cell autophagy, Beclin 1, Human papilloma virus, Klotho;Microtuble associated protein light chain 3

TONG Yan TAN Bu-zhen FANG Yu-ting LAI Zhi-qing WANG Yu WANG Xiao-hong. Related research progress of autophagy in cervical cancer cells[J]. Acta Anatomica Sinica, 2017, 48(1): 111-114.

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