Abstract:

Objective To study the relationship between physiological iron reserve, anemia and elevated blood glucose in Mosuo population in Yunnan, China. Methods Blood samples were collected from 187 Mosuo people in Ninglang County, Yunnan Province, and their glycated hemoglobin (HbA1c), transferrin receptor (TfR) and hemoglobin levels (Hb) were measured. Logistic Regression analysed the relationship between iron status and elevated blood glucose in Mosuo data and Chinese national data (CHNS). Results Compared with the control group, Mosuo people were deficient in iron without anemia, ie iron deficiency erythropoiesis (IDE) corresponds to an increase in the risk of elevated blood glucose (OR=2.70), which is consistent with national data for China. The results of the analysis are consistent.  Conclusion Compared with healthy people, Mosuo people with iron deficiency anemia and non-iron deficiency anemia, Mosuo people who are deficient in iron without anemia are at risk of rising blood sugar. The body iron level of Mosuo people has reference significance for the risk and control of type 2 diabetes.

Key words: Glycated hemoglobin, Anemia, Elevated blood glucose, Logistic Regression, Dry blood spot transferrin receptor test, Mosuo