Abstract:

Objective To understand the effect of abnormal thyroid function on body composition. Methods Selected course was less than 5 years with thyroid dysfunction disease, after the doctor’s standard advice for medicine and good clinical symptom control, 185 patients with hyperthyroidism (male 72, female 113), 154 patients with hypothro idism (33 male, 121 female) and healthy control group 344 cases (male 92, female 252) were included, the application of biological resistance was used respectively measuring body composition, analysis of limbs, trunk and body fat, the differences between the content of skeletal muscle.
Results In men, the muscle mass in the hyperthyroidism group was significantly lower than that in the control group (P<0.01). There was no significant difference in muscle mass in other groups, and no significant difference in fat mass between the three groups. In women, the muscle mass in all parts except the lower limbs in the hypothroidism group was significantly higher than that in the hyperthyroidism group and the control group (P<0.05), while there was no significant difference in muscle mass between the hyperthyroidism group and the control group. The fat content of all parts except the lower limbs in the hypothyroidism group was significantly higher than that of the healthy control group and the hyperthyroidism group (P<0.05), while there was no significant difference in the fat content of all parts between the healthy control group and the hyperthyroidism group. Conclusion Hyperthyroidism can lead to decrease muscle mass in the trunk of male patients. Hypothyroidism can increase the amount of muscle and fat in the body composition of female patients.

Key words: Hyperthyroidism, Hypothyroidism, Body composition, Skeletal muscle content, Fat content, Bioelectrical impedance method, Adult