Relationship of pathogenesis between ischemic stroke and vascular dementia

doi:10.16098/j.issn.0529-1356.2021.05.025

Abstract

Abstract:

Ischemic stroke could cause brain damage and subsequent cognitive or behavioral disorders. Studies have shown that ischemic stroke is a risk factor of vascular dementia, involving common pathophysiological processes and similar risk factors, which are related in pathogenesis, including endothelial dysfunction and the disrupted blood-brain barrier permeability. Micro infarct, microvascular changes, brain atrophy and neurodegenerative changes may be the pathological mechanism of secondary vascular dementia. However, the specific mechanism of the two is still not fully clarified, which will become the focus of future research.

Key words: Ischemic stroke, Vascular dementia, Pathogenesis, Blood brain barrier

CLC Number:

R322.81

SHI Qian-yu CHENG Quan-cheng CHEN Chun-hua. Relationship of pathogenesis between ischemic stroke and vascular dementia[J]. Acta Anatomica Sinica, 2021, 52(5): 834-838.

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