Role of microRNAs in liver regeneration

doi:10.16098/j.issn.0529-1356.2017.02.020

Abstract

Abstract:

microRNAs (miRNAs) are a group of endogenous, small, noncoding RNA molecules which can regulate gene expression at posttranscriptional level by binding to the 3’ untranslated regions (3’UTRs) of their target mRNAs. It has been reported that miRNAs regulated a variety of biological processes, including cell proliferation, differentiation, apoptosis, metabolic process，organ development，etc. Liver as one of the organs with extraordinary regenerative abilities, is considered to be an important material for the research of regeneration mechanism. This paper summarized the research advance of the role of microRNAs in liver regeneration.

Key words: microRNAs, Liver regeneration, Hepatocyte proliferation

ZANG Xia-yan GENG Xiao-fang ZHANG Chun-yan XU Cun-shuan. Role of microRNAs in liver regeneration[J]. Acta Anatomica Sinica, 2017, 48(2): 230-235.

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