Acta Anatomica Sinica ›› 2018, Vol. 49 ›› Issue (3): 395-399.doi: 10.16098/j.issn.0529-1356.2018.03.021

• Review • Previous Articles     Next Articles

Research progress of neuron specific enolase in development,injury and repair of the central nervous system

ZHOU Jing-ying ZHANG Song-ou MENG Xiao-fang LIU Xue-hong*   

  1. Histology and Embryology Department, Medical College of Shaoxing University, Zhejiang Shaoxing 312000, China
  • Received:2017-05-17 Revised:2017-06-17 Online:2018-06-06 Published:2018-09-18
  • Contact: LIU Xue-hong E-mail:liuxueh6588@126.com

Abstract:

As a specific marker of neuron development and reconstruction, neuron specific enolase (NSE) expresses the spatiotemporal distribution in the development and repair of central nervous system. The change of NSE after central nervous system injury can reflect the pathological changes, and can adjust the level of NSE to achieve the effect of post injury repair. It is important for the repair and damage of the nervous system. In this review, we review the molecular structure, expression regulation, biological function of NSE and its relationship with the development, injury and repair of the central nervous system.

Key words: Central nervous system, Neuron specific enolase, Development, Injury, Repair