Objective  To investigate the prevalence rate and biochemical characteristics of hypertension in Zhuang-Dong ethnic groups in China.    Methods  Blood pressure and biochemical indexes were measured in 7411 cases (3248 males and 4163 females) from 5 ethnic groups of Zhuang-Dong nationality.    Results  The difference of crude prevalence rate of hypertension among Zhuang-Dong language groups was statistically significant. The crude prevalence of hypertension in males of the same age group was higher than that in females. Systolic blood pressure and diastolic blood pressure in males and females increased with age, and the crude prevalence of hypertension also increased with age. The mean values of triglyceride, cholesterol and low density lipoprotein in males of Zhuang-Dong language group were all lower than those of females. The mean levels of blood uric acid, blood urea and blood lipid in hypertensive patients were significantly higher than those with normal blood pressure; the mean levels of bilirubin and serum protein in hypertensive patients were close to those with normal blood pressure; the mean levels of blood lipid in hypertensive patients were more than the normal range.     Conclusion  The prevalence of hypertension in Zhuang-Dong ethnic group is high. The patients with hypertension should pay attention to the increase of blood uric acid, blood urea and blood lipid.