Effects of cervical rotatory manipulation on severe rabbit carotid atherosclerosis in flow sheer stress

doi:10．16098/j.issn.0529－1356．2019．06．018

Abstract

Abstract:

Objective　To investigate the effects of cervical rotatory manipulation (CRM) on severe carotid atherosclerosis of rabbits in hemodynamics. 　Methods　Totally 40 New Zealand rabbits were divided randomly into 3 groups, including the manipulation group, the model group and the control group. Left carotid atherosclerotic plaques models were developed in the rabbits of manipulation group and model group. Then, the manipulation group was treated with CRM lasting for 2 weeks; meanwhile no intervention was given on rabbits in the model group and control group. At the end of manipulation, flow sheer stress (FSS) was calculated with velocity and viscosity of blood. One way ANOVA and LSR-t test　were performed to explore the significance. 　Results　FSS of left carotid artery in rabbit decreased significantly in the manipulation group and the model group, in comparison with the control group. Moreover, FSS in the manipulation group was lower than that in the model group. 　Conclusion　FSS of severe atherosclerotic carotid artery in rabbit may become decreased following with CRM.

GUAN Tai－yuan QI Ji LIU Yang XU Yan-xiao WU Kai ZHANG Shao-qun CHEN Yi-li ZHANG Lei. Effects of cervical rotatory manipulation on severe rabbit carotid atherosclerosis in flow sheer stress[J]. Acta Anatomica Sinica, 2019, 50(6): 800-804.

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