解剖学报

›› 2006, Vol. 37 ›› Issue (6): 677-680.doi:

• 论著 • 上一篇    下一篇

白细胞介素-1β及其Ⅰ型受体mRNA在大鼠颈动脉体中的表达

王曦;张西京;李鑫等   

  1. 1第四军医大学神经科学研究所; 2西京医院麻醉科，西安 710032; 3山东大学口腔医学院，济南 250012
  • 收稿日期:2005-11-01 修回日期:2006-04-17 出版日期:2006-12-06
  • 通讯作者: 王百忍

Expressions of IL-1β and IL-1 RI mRNA in the Rat Carotid Body

  1. (1Institute of Neuroscience; 2. Department of Anesthesiology, the Fourth Miliary Medical University, Xi′an 710032, China; 3Stomatological College, Shandong University, Ji′nan 250012, China
  • Received:2005-11-01 Revised:2006-04-17 Online:2006-12-06
  • Contact: WANG Bai-ren

关键词: 白细胞介素-1β, 白细胞介素-1受体Ⅰ型 mRNA, 颈动脉体, 原位分子杂交, 免疫荧光, 免疫印迹法, 大鼠

Abstract: Objective To study the expressions of IL-1 receptor type-Ⅰ(ΒIL-1RI) mRNA and IL-1β protein in the rat carotid body. Methods In situ hybridization, immunofluorescence double staining and Western blotting methods were used. Results The result of in situ  hybridization showed that the positive signal of IL-1β mRNA was mainly located in the glomus cells of the carotid body. The result of immunofluorescence double staining showed that IL-1β protein also expressed in the glomus cells of the organ. The Western blotting proved that the IL-1β immunoreactive band appeared at 18?kD, consi

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