解剖学报 ›› 2014, Vol. 45 ›› Issue (4): 573-577.doi: 10.3969/j.issn.0529-1356.2014.04.024

• 人类学 • 上一篇    下一篇

兰州汉族等26个群体Y-STR基因座遗传的关系

杨鑫1,2孙红兵1,2*骆继怀1,2哈飞1,2张子龙1   

  1. 1. 甘肃省证据科学技术研究与应用重点实验室, 兰州 730070; 2. 兰州市公安局刑事科学技术研究所, 兰州 730030
  • 收稿日期:2013-10-14 修回日期:2014-03-07 出版日期:2014-08-06 发布日期:2014-08-06
  • 通讯作者: 孙红兵 E-mail:lz.yangxin@gmail.com
  • 基金资助:

    国家自然科学基金项目;兰州市科技计划基金资助项目;甘肃省省青年科技基金项目

Genetic relationship among twenty-six populations using Y-STR polymorphism information

YANG Xin 1,2 SUN Hong-bing 1,2* LUO Ji-huai 1,2  HA Fei 1,2 ZHANG Zi-long1   

  1. 1. Experiment Management Center of Gansu Political Science and Law Institute, Lanzhou 730070, China; 2. Forensic Science Institute of Lanzhou Public Security, Lanzhou 730030, China)
     
  • Received:2013-10-14 Revised:2014-03-07 Online:2014-08-06 Published:2014-08-06
  • Contact: SUN Hong-bing E-mail:lz.yangxin@gmail.com

摘要:

目的 探讨兰州汉族等26个人群Y-STR基因座遗传关系。方法 研究得到500名无关兰州汉族个体的Y-STR基因座基因频率,同时收集其他25个人群相同Y-STR基因座基因频率,应用亲缘系数比较分析这26个人群间的遗传距离并绘制系统树。 结果 汉族人群中以北京汉族、山西汉族、内蒙古汉族和与兰州汉族的遗传关系最接近;少数民族人群中以内蒙古蒙古族与兰州汉族的遗传关系最接近;马来西亚马来人和马来西亚印度人与其他人群遗传关系最远而单独列支。结论 利用Y-STR基因座的等位基因频率研究不同人群之间的遗传距离,结果与其他分子人类学结论接近或吻合,表明不同人群之间的遗传关系与地域、起源和进化的关系密切。

关键词: Y-STR基因座, 遗传距离, 分子人类学, 兰州, 汉族

Abstract:

Objective To study the genetic relationship of the Y chromosomal short tandem repeat gene loci in Lanzhou Han population and other 25 populations. Methods The frequency of alleles of Y-STRloci was obtained from a sample of 500 unrelated individuals living in Lanzhou City, and other 25 populations in different areas collected from the published data were used to calculate the genetic similarity coefficient and genetic distance. Phylogenetic trees based on the genetic distance were established. Results Populations of Lanzhou, Beijing, Shanxi and Inner Mongolia were in an identical cluster. Compared with minorities, the genetic distance between Lanzhou Han population and Inner Mongolia Mongolian population was dramatically smaller from other subpopulations. The populations in Malays and Indians were far from the other groups. Conclusion The Y-STR gene frequency distribution in 26 populations has identified differentiation in race, clime and evolution, and it is basically identical with the classification of human races which is similar to or according with other molecular anthropology research conclusions.

Key words: Y-STR loci, Genetic distance, Molecular anthropology,  , Lanzhou, Han population