Analysis of environmental factors influencing on growth and development of plateau children and adolescents in China

doi:10.16098/j.issn.0529-1356.2018.06.013

Abstract

Abstract:

Objective To answer the question of how much environmental factors influence growth and development (GD). Methods Height, weight and chest circumference of 107 986 healthy children and adolescents(CA) aged 7-18 years old living in 14 provincial capital cities of China, and natural and social environmental variables of the cities were collected to study the impact of environmental factors on GD. Results Four body mass index were related to GDP per capita (GDPpc), adult literacy rate (ALR), life expectancy(LE), life expectancy index(LEI), education index(EI), GDP index(GDPI) and human development index(HDI) (P<0.01). Three principal components accounted for 82.75% of the variations. Comprehensive enrollment rate (CER) of college, middle and primary schools, HDI, altitude were the three main influencing factors on GD. Conclusion Altitude is essential in influencing factors on GD of CA and it representes a group of influencing factors. Social environmental variables for GD of CA play an important role, in which education is more outstanding.

Key words: Altitude, Growth, Development, Environment, Child, Adolescent

XI Huan-jiu LI Wen-hui WEN You-feng LIU Kun REN Fu ZHAO Li-guang. Analysis of environmental factors influencing on growth and development of plateau children and adolescents in China[J]. Acta Anatomica Sinica, 2018, 49(6): 770-781.

References

［1］ Gupta R, Basu A, Pawson IG, et al. Altitude and Human Biology: a comparative study of Himalayan, Andean and Ethiopian data. In: Basu A, Gupta R, editors. Human biology of Asian highland populations in the global context［M］. Caltutta: Indian Anthropological Society. 1989: 1-80.

［2］ Leonard WR, Leatherman TL, Carey JW, et al. Contributions of nutrition versus hypoxia to growth in rural Andean populations［J］. Am J Hum Biol, 1990, 2(6):613-626.

［4］ Leatherman TL, Carey JW, Thomas RB. Socioeconomic change and patterns of growth in the Andes［J］. Am J Phys Anthropol,1995, 97(3):307-321.

［5］ Ji Chy. Growth characteristics of Chinese urban youth and the environmental affective factors upon them［J］. Sports Science, 1999,12(5):42-47. (in Chinese).

［6］ Zhang TCh, Zhang FL. Effects of environmental factors on Chinese urbon 18-year-old student growth［J］. Journal of Shandong Institute of Physical Education and Sports, 2011, 27(11): 55-58.(in Chinese).

［7］ Lin WSh, Hu ChK. Study on environment difference of growth and development of Chinese Youth［J］. Acta Sinica Anthrotopca, 1990,9(2):152-159. (in Chinese)

［8］ Little BB, Malina RM, Pena Reyes ME, et al. Altitude effects on growth of indigenous children in Oaxaca, Southern Mexico［J］. Am J Phys Anthropol, 2013,152(1):1-10.

［9］ Weitz CA, Garruto RM, Chin CT, et al. Morphological growth and thorax dimensions among Tibetan compared to Han children,adolescents and young adults born and raised at high altitude［J］. Ann Hum Biol, 2004,31(3):292-310.

［10］ Dittmar M. Linear growth in weight, stature, sitting height and leg length, and body proportions of Aymara school-children living in a hypoxic environment at high altitude in Chile［J］. Z Morphol Anthropol, 1997,81(3):333-344.

［11］ United Nations Development Program. UNDP Human Development Report 2005-International Cooperational a Crossroads: Aid, Trade and Security in an Unequal World［R］. United Nations Development Program, 2005.

［12］ Ministry of Education of PRC, Sports General Administration of the PRC, Ministry of Health of The PRC, et al. Student Physique and Health Survey Report in 2010［M］.Beijing:Higher Education Press, 2010:81-101. (in Chinese)

［13］ Greksa LP. Growth and development of Andean high altitude residents［J］. High Alt Med Biol, 2006,7(2): 116-124.

［14］ Peng Y, Yang Z, Zhang H, et al. Genetic variations in Tibetan populations and high-altitude adaptation at the Himalayas［J］. Mol Biol Evol, 2011,28(2):1075-1081.

［15］ Frisancho AR. Developmental functional adaptation to high altitude: review［J］. Am J Hum Biol, 2013,25(2):151-168.

［16］ Frisancho AR, Baker PT. Altitude and growth: a study of the patterns of physical growth of a high altitude Peruvian Quichua population［J］. Am J Phys Anthropol, 1970,32(2):279-292.

［17］ Xi H, Chen Z, Li W, et al. Chest circumference and sitting height among children and adolescents from Lhasa, Tibet compared to other high altitude populations［J］. Am J Hum Biol. 2016,28(2):197-202.

［18］ Bigham A, Bauchet M, Pinto D, et al. Identifying signatures of natural selection in Tibetan and Andean populations using dense genome scan data［J］. PLoS Genet, 2010, 6(9):e1001116.

［19］ Xi HJ, Wen YF, Zhang HL, et al. Comparative study of the height, weight and chest circumference of children and adolescents between the Tibetan Plateau and the Andes［J］. Acta Anthropologica Sinica, 2014,33(2):198-213. (in Chinese)

［20］ Martorell R. Interrelationships Between diet, Infectious Disease, and Nutritional Status. In: Greene LS, Johnston FE. (eds): Social and Biological Predictors of Nutritional Status, Physical Growth and Neurological Development［M］. New York: Academic Press, 1980: 81-101.

［21］ Frisancho AR, Velasquez T, Sanchez J. Influence of developmental adaptation on lung function at high altitude［J］. Hum Biol, 1973, 45(4):583-594.

［22］ Eveleth PB, Tanner JM. Worldwide Variation in Human Growth［M］. New York: Cambridge University Press,1990:35-55.

［23］ Pawson IG, Huicho L. Persistence of growth stunting in Peruvian high altitude community, 19641999［J］. Am J Hum Biol,2010, 22(3): 367-374.

［24］ Xiao YJ, Xi HJ. Investigation on physique development of Tibetan students aged 7-18 years old in Tibet［J］. Chinese Journal of School Health, 2007, 28(11):968-970. (in Chinese)

［25］ Mueller WH, Schull VN, Schull WJ, et al. A multinational Andean genetic and health program: growth and development in a hypoxic environment［J］. Ann Hum Biol, 1978, 5(4):329-352.

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