Advances in the application of microfluidic technology in assisted reproduction

doi:0.16098/j.issn.0529-1356.2021.02.026

Abstract

Abstract:

The field of assisted reproductive technology (ART) has made rapid progress. Due to the complicated procedures in clinical practice, such as sperm sorting, oocyte selection, fertilization, embryo culture and embryo monitoring, there is still a need for further improvement in efficiency and clinical decision-making. Microfluidic technology is not only a technical means but also a science, which studies the behavior characteristics of fluid at the sub-microlevel. The pipeline and detection terminal of the detection system have great flexibility and can be applied to different detection purpose. It has high detection accuracy and saves the size of samples. It has the characteristics of high integration and matches the detection needs in the practice of assisted reproduction. The application of microfluidic technology can evaluate the basic biological information such as the structure, function and environment of spermatozoa, oocytes and preimplantation embryos, and make accurate and effective coping lans and clinical decisions. This paper reviews the application of microfluidic technology in assisted reproduction, in order to promote the application and improvement of microfluidic technology in the field of reproduction.

Key words: Assisted reproductive technology, Oocyte, Embryo, Sorting, Microfluidics

CLC Number:

O658

WANG Zhong-li WANG Qi DENG Juan LEI Lan-jie YANG Lei. Advances in the application of microfluidic technology in assisted reproduction[J]. Acta Anatomica Sinica, 2021, 52(2): 323-328.

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