Distribution and morphological features of the somatostatin positive neurons in the rat striatum

doi:10.16098/j.issn.0529-1356.2015.05.003

Abstract

Abstract:

Objective To explore the distribution of somatostatin (SOM) in the striatum of the adult rat. Methods SOM expressions in the six adult rats were localized using immunohistochemistry (ABC method). Results In the rat striatum, SOM positive neurons, yellow brown in color, had strong or moderate immunoreactivity and were mainly distributed in cytoplasm and cytoplasmic processes. Somas were in medium size（111.81±21.42）μm², and oval orpolygonal in shape. The dosal SOM immunoreactive neurons（113.52±22.36）μm² were larger than the ventral (110.14±20.59)μm². The outside SOM immunoreactive neurons（126.23±23.45）μm²were larger than the inside（97.26±23.63）μm². SOM immunoreactive neurons were distributed in the ventral medial side（28.34±3.20）％, dorsal-medial region (27.64±3.52)％, ventral-lateral region（24.98±3.17）％, and dorsal-lateral region（19.04±3.12）％. Conclusion The number and size of SOM immunoreactive neurons differ, unveiling the role of SOM in the neural circuits of striatum and providing some morphological basis.

Key words: Somatostatin, Striatum, Immunohistochemistry, Rat

ZHANG Wen-jun YU Ming-yuan WANG Li-li TENG Ke-dao MA Yun-fei*. Distribution and morphological features of the somatostatin positive neurons in the rat striatum[J]. AAS, 2015, 46(5): 591-595.

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