Acta Anatomica Sinica ›› 2022, Vol. 53 ›› Issue (2): 266-272.doi: 10.16098/j.issn.0529-1356.2022.02.019

• Review • Previous Articles    

Advances in biological functions of miR-429

GUO Jian-lin1.2*  WANG Xue-qing1.2  XU Cun-shuan1,2*   

  1. 1.College of Life Science,He’nan Normal University,He’nan Xinxiang 453007,China; 2.State Key Laboratory Cultivation Base for Cell Differentiation Regulation,He’nan Normal University,He’nan Xinxiang 453007,China
  • Received:2020-09-29 Revised:2020-11-28 Online:2022-04-06 Published:2022-04-06
  • Contact: GUO Jian-lin;XU Cun-shuan E-mail:gjianlin@yeah.net

Abstract:

MicroRNAs (miRNAs, miR) are endogenous non-coding single-stranded RNAs with a length of about 22 nucleotides. These RNAs play an important biological function within cells, among which, miR-429 has been proved to play an important role in inhibiting tumor development and tumor progression as well as in cell differentiation and neurological diseases by regulating the expression of different target genes. In this paper, the role of miR-429 and its downstream targeted genes in cell proliferation, apoptosis, migration and invasion is summarized.

Key words: MicroRNA-429, Biological function, Cell proliferation, Cell migration, Cell invasion

CLC Number: