高龄女性移植2枚或3枚卵裂期胚胎的临床效果比较

doi:10.16098/j.issn.0529-1356.2021.01.018

解剖学报 ›› 2021, Vol. 52 ›› Issue (1): 113-117.doi: 10.16098/j.issn.0529-1356.2021.01.018

• 组织学胚胎学发育生物学 • 上一篇下一篇

高龄女性移植2枚或3枚卵裂期胚胎的临床效果比较

付磊周雯慧*

首都医科大学附属北京朝阳医院生殖医学中心，北京 100020

收稿日期:2019-07-24 修回日期:2019-09-10 出版日期:2021-02-06 发布日期:2021-02-06
通讯作者: 周雯慧 E-mail:wenhuizhbjcy@126.com
基金资助:
国家自然科学基金;北京市医管局临床技术创新项目;北京朝阳医院朝阳新星计划

Comparison of clinical outcome between 2 and 3 embryos transfer for elderly women

FU Lei ZHOU Wen-hui*

Medical Center for Human Reproduction, Beijing Chao-Yang Hospital, Capital Medical University, Beijing 100020, China

Received:2019-07-24 Revised:2019-09-10 Online:2021-02-06 Published:2021-02-06
Contact: ZHOU Wen-hui E-mail:wenhuizhbjcy@126.com

摘要/Abstract

摘要：

目的探讨移植2枚或3枚胚胎与临床结局的关系，为高龄女性胚胎移植数的选择提供依据。方法对80个卵裂期胚胎新鲜移植周期进行回顾性分析，根据移植胚胎数将这些周期分组，并对各组的临床妊娠率、种植率、多胎妊娠率及活产率进行比较。

结果对于年龄≥38岁的女性，当可利用胚胎数≥3枚时，移植2枚胚胎与移植3枚胚胎能够获得相似的临床妊娠率及活产率。这一趋势与所移植的8细胞胚胎数无关。结论高龄女性新鲜卵裂期胚胎移植数目不宜超过2枚。

关键词: 人类辅助生殖, 卵裂期胚胎移植, 移植胚胎数, 临床结局, 体外受精, 高龄女性

Abstract:

Objective To explore the relationship between clinical outcomes and embryo transfer number, and to provide some proposals for transfer selection of elderly patients. Methods Data from 80 fresh transfer cycles with cleavage-stage embryos were analyzed. Cycles were divided into several groups according to transfer number. Clinical pregnancy rate, implantation rate, multiple pregnancy rate and live birth rate were compared. Results To women no younger than 38 years old, when available embryo number was larger than two, similar clinical outcomes could be achieved by transferring two and three embryos. This trend was independent of the number of transferred 8-cell embryos. Conclusion The number of fresh cleavage-stage embryos transfer should not exceed two in elderly women.

Key words: Human assisted reproduction, Cleavage-stage embryo transfer, Transfer number, Clinical outcome, In vitro fertilization, Elderly woman

中图分类号:

R322.81

付磊周雯慧. 高龄女性移植2枚或3枚卵裂期胚胎的临床效果比较[J]. 解剖学报, 2021, 52(1): 113-117.

FU Lei ZHOU Wen-hui. Comparison of clinical outcome between 2 and 3 embryos transfer for elderly women[J]. Acta Anatomica Sinica, 2021, 52(1): 113-117.

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高龄女性移植2枚或3枚卵裂期胚胎的临床效果比较

Comparison of clinical outcome between 2 and 3 embryos transfer for elderly women

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