›› 2009, Vol. 40 ›› Issue (2): 303-306.doi: 10.3969/j.issn.0529-1356.2009.02.027

• 论著 • 上一篇    下一篇

小鼠子宫内膜中鸡冠珊瑚树凝集素和双花藕豆凝集素受体在胚泡植入过程中的表达

秦迎1;秦良2;刘凯3;孙英1   

  1. 1.山东医学高等专科学校解剖学教研室,济南 250002; 2.滕州市中心人民医院功能检查科,山东 滕州 277500;3.山东大学医学院组织学与胚胎学教研室,济南 250012
  • 收稿日期:2007-08-23 修回日期:2008-01-16 出版日期:2009-04-06
  • 通讯作者: 刘凯

Expression of the receptors for the lection ECL and DBA in mouse endometrium during implantation

  1. 1.Department of Anatomy, Shandong Medical College, Ji′nan 250002, China;2Department of Function Examination, the Central People’s Hospital of Tengzhou, Shandong Tengzhou 277500, China; 3. Department of Histology and Embryology of Medical College, Shandong University, Ji′nan 250012, China
  • Received:2007-08-23 Revised:2008-01-16 Online:2009-04-06
  • Contact: LIU Kai

关键词: 植入, 凝集素受体, 子宫内膜, 亲和细胞化学, 小鼠

Abstract: Objective To explore the relationship between implantation and the receptors for erythrina cristagalli lectin (ECL) and dolichos biflorus agglutinin (DBA) distributed in mouse endometrium. Methods During early pregnancy, ECL and DBA marked by biotin were used to observe the distribution and change in 2 kinds of lectin receptors in pregnant and nonfertile mouse endometrium. Results On the pregnant side, the ECL receptor is mainly distributed in the trophoblast and its basement membrane, the surface of the decidual cells and their surrounding extracellular matrix(ECM). On the nonfertile side, the lectin receptor is mainly expressed on the superficial surface of the endometrial epithelium and uterine gland epithelium. On the pregnant side, the DBA receptor is mainly expressed in the trophoblast and its basement membrane and the basement membrane of blood vessels. However, on the nonfertile side, the DBA receptor is mainly in the basement membarane of blood vessels.Conclusion The receptors for ECL and DBA play a key roles during blastocyst implantation in mice.

Key words: Implantation, Lection receptor, Endometrium, Affinity cytochemistry, Mouse

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