解剖学报

›› 2010, Vol. 41 ›› Issue (4): 603-605.doi: 10.3969/j.issn.0529-1356.2010.04.023

• 论著 • 上一篇    下一篇

膜联蛋白A7在人宫颈鳞癌和正常组织中的表达

陈雪1; 高福禄1*; 常彦忠2;段相林2 ;李欣3   

  1. 1.河北医科大学组织学胚胎学教研究，石家庄 050017; 2.河北师范大学生命科学学院，石家庄 050016;3.承德医学院组织学胚胎学教研究，河北 承德 067000
  • 收稿日期:2009-09-23 修回日期:2009-10-26 出版日期:2010-08-06
  • 通讯作者: 高福禄

Expression of annexin A7 in human uterine cervical squamous carcinomas and normal tissues

  1. 1.Department of Histology and Embryology,Hebei Medical University, Shijiazhuang 050017,China;2.Colloge of Life Sciences,Hebei Normal University, Shijiazhuang 050016,China;3.Department of Histology and Embryology, Chengde Medical College, Hebei Chengde 067000,China
  • Received:2009-09-23 Revised:2009-10-26 Online:2010-08-06
  • Contact: GAO Fu-lu

关键词: 膜联蛋白A7, 宫颈鳞癌, 免强印迹法, 反转录-聚合酶链式反应, 人

Abstract: Objective To detect the expression of annexin A7 in human uterine cervical squamous cell carcinoma tissues and normal tissues. Methods SP immunohistochemistry was used to observe the differential expression of annexin A7 between carcinoma and normal paraffin imbedded specimen, each 25 cases. Western blotting and RT-PCR were used to observe the differential expression of annexin A7 between human uterine cervical squamous cell carcinoma and normal fresh tissues,each 25 cases. Results The annexin A7 expression in the tumor tissues was much higher than that of the normal tissues at the protein and the mRNA levels (P<0.05). Conclusion The expression of annexin A7 is upregulated in human uterine cervical squamous cell carcinoma tissues and it might be a new valuable tumor marker.

Key words: Annexin A7, Uterine cervical squamous carcinoma, Western boltting, RT-PCR, Human

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