Advances of mechanism and function of bone vascularization

doi:10.16098/j.issn.0529-1356.2019.05.027

Abstract

Abstract:

The vascular system in bone not only provides oxygen and nutrients to highly anabolic skeletal cells, but also participates in the process of bone formation and bone regeneration. Based on morphological and physiological characteristics, two subtypes of bone capillaries can be distinguished. Endothelial cells and osteoprogenitor cells influence each other by secreting specific growth factors, which have an important role in the coupling of angiogenesis and osteogenesis. A greater understanding of the architecture of the bone vasculature and the angiogenic response may contribute to enhanced bone regeneration.

Key words: Bone, Angiogenesis, Fracture healing

LI Xu CHEN Yi-min WANG Ding-yu SHEN Zhong-cheng ZHANG Wei-guang. Advances of mechanism and function of bone vascularization[J]. Acta Anatomica Sinica, 2019, 50(5): 703-706.

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