AAS ›› 2014, Vol. ›› Issue (2): 171-175.doi: 10.3969/j.issn.0529-1356.2014.02.005

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Distribution characteristics of follicle-stimulating hormone receptor in the cervicothoracic ganglion of goat

JIN Xiu-fang WANG Zhi-hao FAN Jie XU Yong-ping* CHEN Wen-dong GUO Xiao   

  1. Basic Anatomy Laboratory,College of Veterinary Medicine, Northwest A&F University, Shanxi Yangling 712100, China
  • Received:2013-03-26 Revised:2013-05-06 Online:2014-04-06 Published:2014-04-06
  • Contact: XU Yong-ping E-mail:xuyp717@yahoo.com.cn

Abstract:

Objective To investigate whether follicle stimulating hormone (FSH) affects autonomic regulation of cardiopulmonary function. Methods Five pairs of cervicothoracic ganglion were taken from mature female and male gosts. The distribution of follicle stimulating hormone receptor (FSHR) in the cervicothoracic ganglion of the goat was observed after immunohisto-chemical SP staining. Results FSHR immunoreactive substances mainly distributed in neurons’ cytoplasm and membrane, but not in the nucleus. There was some expression of FSHR in surrounding supporting cells, passing fibers,Schwan cells and vascular endothelial cells. Image analysis showed that the relative expression of immunoreactive product FSHR was significantly higher than that of other nonneural structures(P<0.01). Conclusion These results suggest that the neurons in cerricothoracic ganglion are the main target cells of FSH in goats and FSH is likely to affect neurons of the cervicothoracic ganglion and then further to regulate cardiopulmonary function activities via the postganglionic sympathetic nerve.