Progress of blood cells reprogramming to induced pluripotent stem cells

doi:10.16098/j.issn.0529-1356.2015.06.022

Abstract

Abstract:

Induced pluripotent stem cells (iPSCs) technology can revert differentiated cells to pluripotent cells and avoid the limitation such as ethics, immunerejection. It has broad applications in the field of regenerative medicine. Although induced pluripotent stem cells have already set up for all sorts of donor cells, the application in clinical facilities and induction of donor origin still has various limitations. In this review, we discuss the characteristics, advantages and applications of utilizing blood cells as donor cells for reprogramming, providing a theoretical basis for the ultimate applications of induced pluripotent stem cells in clinical studies.

Key words: Blood cell, Induced pluripotent stem cell, Reprogramming, Application

ZHANG Yue WU Bin GONG Tian-tian LEI Lei SHAN Zhi-yan*. Progress of blood cells reprogramming to induced pluripotent stem cells[J]. AAS, 2015, 46(6): 852-856.

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