AAS ›› 2013, Vol. 44 ›› Issue (4 ): 456-462.doi: 10.3969/j.issn.0529-1356.2013.04.003

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N-methyl-D-aspartate receptor 2A expression intensity in brain regions of adult male SD rats

BI Wen-jie XIAO Li ZHENG Xiang 2*   

  1. 1. Department of Anatomy, Chengdu Medical College, Chengdu 610083,China; 2. Laboratory of Preclinical Medicine,West China School of Preclinical Medicine and Forensic Medicine, Sichuan University, Chengdu 610041, China
  • Received:2012-05-07 Revised:2012-08-13 Online:2013-08-06 Published:2013-09-04

Abstract:

Objective N-methyl-D-aspartate receptor (NMDAR) is an important excitatory receptor within the central nervous system. Its 2A subunit is a critical functional subunit. There is no comprehensive data about NMDAR 2A expression intensity
in rat brain. Methods In this experiment, we detected NMDAR 2A expression in the brain of adult male SD rat (n=6) with immunohistochemistry staining and image analysis. Results We drew the expression intensity atlas of rat brain based on the
immunohistochemical staining intensity. Conclusion These data can provide a reference for in situ detection of NMDAR 2A in related experiments.

Key words: Brain, N-methyl-D-aspartate receptor 2A, Immunohistochemistry, Rat

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