Acta Anatomica Sinica ›› 2019, Vol. 50 ›› Issue (5): 677-683.doi: 10.16098/j.issn.0529-1356.2019.05.023

Previous Articles     Next Articles

Progress in the therapeutic use of methylene blue in ischemic stroke

ZHANG Meng-qin1 LU Jian-fei2 CHEN Chun-hua 1*   

  1. 1. Department of Human Anatomy and HistoEmbryology, School of Basic Medical Sciences, Peking University Health Science Center,Beijing 100083, China; 2. Department of Anatomy and Physiology, Shanghai Jiao Tong University College of Basic Medical Sciences,Shanghai 200025, China
  • Received:2018-10-23 Revised:2018-11-22 Online:2019-10-06 Published:2019-12-10
  • Contact: CHEN Chun-hua E-mail:cch@bjmu.edu.cn

Abstract:

Stroke has been widely studied as a highly lethal and highly disabling disease worldwide. Methylene blue approved by the Food and Drug Administration(FDA) of the United States has been used in the treatment of methemoglobinemia and cyanide poisoning for more than one hundred and twenty years. In recent studies, it has been found to have neuroprotective effects and is effective in a few of animal models of ischemic stroke. This article briefly reviews the recent research on the therapeutic use of methylene blue in ischemic stroke.

Key words: Methylene blue, Ischemic stroke, Neuroprotection