土尔扈特人Y染色体分子遗传学特征

doi:10.16098/j.issn.0529-1356.2018.06.018

摘要/Abstract

摘要：

目的探讨土尔扈特人Y染色体分子遗传学特征。方法采用随机取样方法，遵循知情同意和伦理学原则，于2015年9月在内蒙古自治区额济纳旗采集了49例土尔扈特人外周静脉血5 ml。对49份样本Y染色体17个Y-STR位点进行复合扩增检测，获得每份样本的基因分型数据，应用Past v2.17和NetWork 11.0统计学软件对数据进行分析。结果土尔扈特人主要的单倍群是C3、O3、N、R。土尔扈特人、巴尔虎蒙古族、厄鲁特蒙古族、喀尔喀蒙古族、呼伦贝尔布里亚特人、哈萨克族、达斡尔族、蒙古国蒙古族C3单倍群频率最高。从各单倍群频率的分布来看，土尔扈特人与巴尔虎蒙古族最相近。16个族群基本按地域分开，土尔扈特人接近于呼伦贝尔布里亚特人、巴尔虎蒙古族、厄鲁特蒙古族、喀尔喀蒙古族、哈萨克族、俄罗斯布里亚特人、蒙古国蒙古族。土尔扈特人与东乡族、保安族相距较远。结论土尔扈特人与呼伦贝尔布里亚特人、巴尔虎蒙古族和厄鲁特蒙古族处在相近的进化枝上，具有遗传上的相似性。

关键词: Y染色体, Y-SNP, Y-STR, 主成分分析, 土尔扈特人

Abstract:

Objective To study Y chromosome molecular genetics of Torghut. Methods Using random sampling method and informed consents and ethical principles, venous blood samples, 5 ml each, were collected from 49 cases of peripheral Torghut in september 2015 in the Inner Mongolia Autonomous Region of Ejinaqi. Fourtynine samples of 17 Y chromosome Y-STR loci multiplex PCR were detected, and genotyping data was obtained in each sample gene. The data was analyzed by Past v2.17 and NetWork 11.0 statistical software. Results Torghut mainly haplogroup C3, O3, N, R. C3 haplogroup frequency was the highest in Torghut, Barga Mongolian,??led Mongolian, Khalkh Mongolian, Hulun Buir Buryat, Kazak, Daur and Mongolian in Mongolia. From the frequency distribution of each haplotype, Torghut and Barga Mongolian were most similar. Sixteen groups were seperated according to the geagraphy. Torghut was close to Hulun Buir Buryat, Barga Mongolian, Hulun Buir Buryat, Barga Mongolian, led Mongolian Khalkh Mongolian, Kazak, and Russian Buryat of Mongolia. Torghut was far away from Dongxiang and Baoan. Conclusion Torghut and Hulun Buir Buryat、Barga Mongolian、??led Mongolian on a similar branch, have genetic similarity.

Key words: Y chromosome, Y-SNP, Y-STR, Principal component analysis, Torghut

廉伟李咏兰 . 土尔扈特人Y染色体分子遗传学特征[J]. 解剖学报, 2018, 49(6): 804-808.

LIAN Wei LI Yong-lan . Y chromosome molecular genetics characteristics of Torghut[J]. Acta Anatomica Sinica, 2018, 49(6): 804-808.

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